Frontline Science: Corticotropin-releasing factor receptor subtype 1 is a critical modulator of mast cell degranulation and stress-induced pathophysiology.
Ayyadurai, Saravanan; Gibson, Amelia J; D'Costa, Susan; Overman, Elizabeth L; Sommerville, Laura J; Poopal, Ashwini C; Mackey, Emily; Li, Yihang; Moeser, Adam J.
J Leukoc Biol
; 102(6): 1299-1312, 2017 12.
Artigo em Inglês | MEDLINE | ID: mdl-28684600
Structure modeling using genetically engineered crosslinking.
Genetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCR.
Structure of class B GPCR corticotropin-releasing factor receptor 1.
Binding kinetics redefine the antagonist pharmacology of the corticotropin-releasing factor type 1 receptor.
Quinoxalines as potent selective CRFRs ligands for monitoring and brain diagnostic.
The specific monomer/dimer equilibrium of the corticotropin-releasing factor receptor type 1 is established in the endoplasmic reticulum.
Discovery of a 7-arylaminobenzimidazole series as novel CRF1 receptor antagonists.
Rosetta Broker for membrane protein structure prediction: concentrative nucleoside transporter 3 and corticotropin-releasing factor receptor 1 test cases.
P7, a novel antagonist of corticotropin releasing factor receptor type 1 (CRFR1) screened from phage display library.
Control of stress-induced persistent anxiety by an extra-amygdala septohypothalamic circuit.