Celiac Immunogenic Potential of α-Gliadin Epitope Variants from <i>Triticum</i> and <i>Aegilops</i> Species.
Ruiz-Carnicer, Ángela; Comino, Isabel; Segura, Verónica; Ozuna, Carmen V; Moreno, María de Lourdes; López-Casado, Miguel Ángel; Torres, María Isabel; Barro, Francisco; Sousa, Carolina.
; 11(2)2019 Jan 22.
Artigo em Inglês | MEDLINE | ID: mdl-30678169
Diversification of the celiac disease α-gliadin complex in wheat: a 33-mer peptide with six overlapping epitopes, evolved following polyploidization.
Genetic and environmental factors affecting the expression of α-gliadin canonical epitopes involved in celiac disease in a wide collection of spelt (Triticum aestivum ssp. spelta) cultivars and landraces.
Production and molecular characterization of bread wheat lines with reduced amount of α-type gliadins.
Celiac disease T-cell epitopes from gamma-gliadins: immunoreactivity depends on the genome of origin, transcript frequency, and flanking protein variation.
Experimental evolutionary studies on the genetic autonomy of the cytoplasmic genome "plasmon" in the <i>Triticum</i> (wheat)-<i>Aegilops</i> complex.
Characterization of a dominant mutation for the liguleless trait: Aegilops tauschii liguleless (Lg<sup>t</sup>).
Allelic variations of α-gliadin genes from species of Aegilops section Sitopsis and insights into evolution of α-gliadin multigene family among Triticum and Aegilops.
Characterization of a hypoallergenic wheat line lacking ω-5 gliadin.
Analysis of metabolic pathways related to fertility restoration and identification of fertility candidate genes associated with Aegilops kotschyi cytoplasm in wheat (Triticum aestivum L.).
Tetraploid and hexaploid wheat varieties reveal large differences in expression of alpha-gliadins from homoeologous Gli-2 loci.