Production of monoclonal antibodies for measuring Avastin and its biosimilar by Sandwich ELISA.
Li, Maohua; An, Wenqi; Wang, Lan; Zhang, Feng; Li, Jianli; Zhang, Yongchao; Li, Yingzi; Li, Hongzhen; Ren, Wenlin; Zhao, Rongqing; Xia, Chenxi; Sun, Le.
J Immunol Methods
; 469: 42-46, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30943379
Biosimilars: Hope and concern.
Nonclinical assessments of the potential biosimilar PF-06439535 and bevacizumab.
Pharmacokinetic and toxicology comparator testing of biosimilar drugs - Assessing need.
A new reliable, transposable and cost-effective assay for absolute quantification of total plasmatic bevacizumab by LC-MS/MS in human plasma comparing two internal standard calibration approaches.
A phase I, randomized, single-dose study evaluating the pharmacokinetic equivalence of biosimilar ABP 215 and bevacizumab in healthy adult men.
Antibody drug quantitation in coexistence with anti-drug antibodies on nSMOL bioanalysis.
Development of an LC-MS/MS method with protein G purification strategy for quantifying bevacizumab in human plasma.
Strengths, weaknesses and future challenges of biosimilars' development. An opinion on how to improve the knowledge and use of biosimilars in clinical practice.
The Role of Biosimilars.