Specific RANK Cytoplasmic Motifs Drive Osteoclastogenesis.
Li, Yuyu; Shi, Zhenqi; Jules, Joel; Chen, Shenyuan; Kesterson, Robert A; Zhao, Dongfeng; Zhang, Ping; Feng, Xu.
J Bone Miner Res
; 2019 Jun 07.
Artigo em Inglês | MEDLINE | ID: mdl-31173390
Diphlorethohydroxycarmalol from Ishige okamurae Suppresses Osteoclast Differentiation by Downregulating the NF-κB Signaling Pathway.
Conditioned medium from fresh and demineralized bone enhances osteoclastogenesis in murine bone marrow cultures.
Ubiquitin E3 Ligase LNX2 is Critical for Osteoclastogenesis In Vitro by Regulating M-CSF/RANKL Signaling and Notch2.
Constant hypoxia inhibits osteoclast differentiation and bone resorption by regulating phosphorylation of JNK and IκBα.
Engineering a monomeric variant of macrophage colony-stimulating factor (M-CSF) that antagonizes the c-FMS receptor.
Luman is involved in osteoclastogenesis through the regulation of DC-STAMP expression, stability and localization.
G protein-coupled receptor 84 controls osteoclastogenesis through inhibition of NF-κB and MAPK signaling pathways.
Follistatin-like 1 promotes osteoclast formation via RANKL-mediated NF-κB activation and M-CSF-induced precursor proliferation.
C-Mpl Is Expressed on Osteoblasts and Osteoclasts and Is Important in Regulating Skeletal Homeostasis.
Ganomycin I from Ganoderma lucidum attenuates RANKL-mediated osteoclastogenesis by inhibiting MAPKs and NFATc1.