A systematic review of East African-Indian family of Mycobacterium tuberculosis in Brazil
Braz. j. infect. dis
; 21(3): 317-324, May-June 2017. tab, graf
Article
in English
| LILACS
| ID: biblio-839213
Responsible library:
BR1.1
ABSTRACT
ABSTRACT Introduction:
The Mycobacterium tuberculosis East African-Indian (EAI) spoligotyping family (belonging to lineage 1, Indo-Oceanic, defined by the region of deletion RD239) is distributed worldwide, but is more prevalent in Southeast Asia, India, and East Africa. Studies in Latin America have rarely identified EAI. In this study, we describe the occurrence of the EAI family in Brazil.Methods:
EAI was identified in a systematic literature review of genetic diversity studies pertaining to M. tuberculosis in Brazil, as well as in a survey conducted in Salvador, Bahia, located in the northeastern region of this country.Results:
The EAI6-BGD1 spoligotyping family and the EAI5 Spoligotype International Type (SIT) 1983 clade were the most frequently reported, with wide distribution of this particular clade described in Brazil. The distribution of other EAI spoligotyping patterns with broader worldwide distribution was restricted to the southeastern region of the country.Conclusions:
EAI may be endemic at a low frequency in Brazil, with some clades indicating increased fitness with respect to this population.
Full text:
Available
Collection:
International databases
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Tuberculosis
Database:
LILACS
Main subject:
DNA, Bacterial
/
Bacterial Typing Techniques
/
Mycobacterium tuberculosis
Type of study:
Systematic review
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2017
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal da Bahia/BR