Molecular detection of mixed infections with multiple dengue virus serotypes in suspected dengue samples in Tamaulipas, Mexico
Mem. Inst. Oswaldo Cruz
; 112(7): 520-522, July 2017. tab, graf
Article
in English
| LILACS
| ID: biblio-841817
Responsible library:
BR1.1
ABSTRACT
This study aimed to detect dengue virus (DENV) serotypes in serum samples obtained in Matamoros Tamaulipas, Mexico, and to determine the concordance of conventional nested reverse transcriptase polymerase chain reaction (RT-PCR) and a serological test [enzyme-linked immunosorbent assay (ELISA NS1)]. Here, we detected mixed infections consisting of four serotypes of DENV. The most prevalent serotype was DENV-1, followed by DENV-4. This is the first report of DENV-4 in our region. Mixed infections were also detected in 21.5% of samples, and the predominant coinfection consisted of DENV-1 and DENV-2. Therefore, continuous epidemiological surveillance of DENV in this area is required to predict future forms of dengue heterologous infections and the effect of this on health care.
Full text:
Available
Collection:
International databases
Health context:
Neglected Diseases
Health problem:
Dengue
/
Neglected Diseases
Database:
LILACS
Main subject:
Enzyme-Linked Immunosorbent Assay
/
Polymerase Chain Reaction
/
RNA-Directed DNA Polymerase
/
Dengue
/
Dengue Virus
/
Serogroup
/
Antibodies, Viral
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Humans
/
Male
Country/Region as subject:
Mexico
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2017
Document type:
Article
/
Project document
Affiliation country:
Mexico
Institution/Affiliation country:
Instituto Politécnico Nacional/MX