Epstein-Barr virus: general factors, virus-related diseases and measurement of viral load after transplant
Rev. bras. hematol. hemoter
; 33(5): 383-388, Oct. 2011. tab
Article
in English
| LILACS
| ID: lil-606716
Responsible library:
BR408.1
ABSTRACT
The Epstein-Barr virus is responsible for infectious mononucleosis syndrome and is also closely associated to several types of cancer. The main complication involving Epstein-Barr virus infection, both in recipients of hematopoietic stem cells and solid organs, is post-transplant lymphoproliferative disease. The importance of this disease has increased interest in the development of laboratory tools to improve post-transplant monitoring and to detect the disease before clinical evolution. Viral load analysis for Epstein-Barr virus through real-time polymerase chain reaction is, at present, the best tool to measure viral load. However, there is not a consensus on which sample type is the best for the test and what is its predictive value for therapeutic interventions.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Polymerase Chain Reaction
/
Lymphoproliferative Disorders
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Rev. bras. hematol. hemoter
Journal subject:
Hematology
Year:
2011
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Laboratório Central do Estado do Paraná/BR
/
Universidade Federal do Paraná/BR