Linfocitos T CD4+ y carga viral en pacientes VIH/sida de la tercera edad que reciben tratamiento antirretroviral / CD4+ T-lymphocytes and viral load in elderly patients with HIV/AIDS who receive antiretroviral treatment
Rev. cuba. invest. bioméd
; 32(2): 139-146, abr.-jun. 2013.
Article
in Spanish
| LILACS
| ID: lil-685975
Responsible library:
CU1.1
RESUMEN
Introducción:
La infección por el virus de inmunodeficiencia humana (VIH) constituye un importante problema de salud. La capacidad funcional del sistema inmune declina gradualmente con el envejecimiento.Objetivo:
Demostrar que los pacientes VIH/sida de la tercera edad, tratados con antirretrovirales, presentan disminución de la carga viral y aumento de los linfocitos T CD4+ con el uso del tratamiento.Métodos:
Se realizó un estudio observacional prospectivo de corte transversal en 44 pacientes VIH/SIDA pertenecientes al servicio de Medicina del IPK que recibieron tratamiento con diferentes esquemas de antirretrovirales.Resultados:
Se observó un incremento medio de linfocitos T CD4+ de 97 cel/µL así como una disminución media de carga viral de 3 583 cp/µL después del tratamiento antirretroviral.Conclusiones:
Con este estudio podemos concluir que con el uso de la terapia antirretroviral en los pacientes VIH/sida de la tercera edad aumentaron los linfocitos T CD4+ y disminuyó la carga viral, lo que evidencia la reconstitución inmunológica y el control virológico de estos pacientesABSTRACT
Background:
Infection with the Human Immunodeficiency Virus (HIV) is a major health problem. The functional capacity of the immune system gradually declines with aging.Objective:
To demonstrate that the elderly patients with HIV/AIDS who follow treatment with antiretroviral drugs present a fall in viral load and a rise in the CD4+ T-lymphocytes with this treatment.Methods:
A cross-sectional prospective observational study was conducted in 44 HIV/AIDS patients attended in the Medical Services offered by IPK who received treatment with different antiretroviral schemes.Results:
It was observed that there was an average rise of 97 cel/µL in the CD4+ T-lymphocytes, as well as an average fall of 3 583 cp/µL in viral load after the antiretroviral treatment.Conclusions:
With this study, we can conclude that there was a rise in CD4+ T-lymphocytes and a fall in the viral load in the elderly patients with HIV/AIDS who followed treatment with antiretroviral drugs, what evidences the immunological reconstitution and virologic control of these patients with the use of antiretroviral therapy
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.3: End transmission of communicable diseases
Database:
LILACS
Main subject:
Health of the Elderly
/
HIV
/
Viral Load
/
Anti-Retroviral Agents
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Limits:
Aged
Language:
Spanish
Journal:
Rev. cuba. invest. bioméd
Journal subject:
Medicine
Year:
2013
Document type:
Article
Affiliation country:
Cuba
Institution/Affiliation country:
Universidad de La Habana/CU