Factores de riesgo de ocurrencia y gravedad de malformaciones congénitas / Identification of risk factors for congenital malformations
Rev. méd. Chile
; 142(11): 1431-1439, nov. 2014. ilus, tab
Article
in Spanish
| LILACS
| ID: lil-734879
Responsible library:
CL1.1
ABSTRACT
Background:
The relative importance of congenital malformations as a cause of death in the first year of life is increasing along with the control of preventable causes of perinatal mortality.Aim:
To identify risk factors for congenital malformations. Patients andMethods:
Retrospective case-control study of births registered in the database of The Latin American Collaborative Study of Congenital Malformations (ECLAMC), in the period 2001-2010.Results:
Birth weight and gestational age were significantly lower in cases than controls, behaving as risk factors and associated with a greater severity of congenital malformations. The risk and severity of congenital malformations increased along with mother’s age. Fetal growth retardation, a history of congenital malformations in the family, physical factors and acute illnesses of the mother in the first trimester of pregnancy were also significant risk factors for congenital malformations and their severity. The educational level of the mother was a protective factor for congenital malformations and their severity.Conclusions:
Variables previously identified as risk factors for congenital malformations, were significantly related with the occurrence of congenital malformations and their severity.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
/
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
/
SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5
Health problem:
Target 3.1: Reduce maternal mortality
/
Target 3.2: Reduce avoidable death in newborns and children under 5
/
Congenital and Chromosomal Anomalies
/
Neonatal Healthcare
/
Nutrition
Database:
LILACS
Main subject:
Congenital Abnormalities
Type of study:
Diagnostic study
/
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Male
/
Infant, Newborn
/
Pregnancy
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2014
Document type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Universidad de Chile/CL