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Craniofacial anomalies associated with hypospadias. Description of a hospital based population in South America
Fernandez, Nicolas; Escobar, Rebeca; Zarante, Ignacio.
Affiliation
  • Fernandez, Nicolas; Pontificia Universidad Javeriana. Hospital Universitario San Ignacio. Urología - Genética. Bogota. CO
  • Escobar, Rebeca; Pontificia Universidad Javeriana. Hospital Universitario San Ignacio. Urología - Genética. Bogota. CO
  • Zarante, Ignacio; Pontificia Universidad Javeriana. Hospital Universitario San Ignacio. Urología - Genética. Bogota. CO
Int. braz. j. urol ; 42(4): 793-797, July-Aug. 2016. tab
Article in English | LILACS | ID: lil-794671
Responsible library: BR1.1
ABSTRACT
ABSTRACT

Introduction:

Hypospadias is a congenital abnormality of the penis, in which there is incomplete development of the distal urethra. There are numerous reports showing an increase of prevalence of hypospadias. Association of craniofacial malformations in patients diagnosed with hypospadias is rare. The aim of this study is to describe the association between hypospadias and craniofacial congenital anomalies. Materials and

Methods:

A retrospective review of the Latin-American collaborative study of congenital malformations (ECLAMC) data was performed between January 1982 and December 2011. We included children diagnosed with associated hypospadias and among them we selected those that were associated with any craniofacial congenital anomaly.

Results:

Global prevalence was 11.3 per 10.000 newborns. In this population a total of 809 patients with 1117 associated anomalies were identified. On average there were 1.7 anomalies per patient. Facial anomalies were present in 13.2%. The most commonly major facial anomaly associated to hypospadias was cleft lip/palate with 52 cases. We identified that 18% have an association with other anomalies, and found an association between craniofacial anomalies and hypospadias in 0.59 cases/10.000 newborns.

Discussion:

Hypospadias is the most common congenital anomaly affecting the genitals. Its association with other anomalies is rare. It has been reported that other malformations occur in 29.3% of the cases with hypospadias. The more proximal the meatus, the higher the risk for having another associated anomaly.

Conclusion:

Associated hypospadias are rare, and it is important to identify the concurrent occurrence of craniofacial anomalies to better treat patients that might need a multidisciplinary approach.
Subject(s)


Full text: Available Collection: International databases Database: LILACS Main subject: Population Surveillance / Craniofacial Abnormalities / Hypospadias Type of study: Controlled clinical trial / Prevalence study / Risk factors / Screening study Limits: Humans / Male / Infant, Newborn Country/Region as subject: South America Language: English Journal: Int. braz. j. urol Journal subject: Urology Year: 2016 Document type: Article Affiliation country: Colombia Institution/Affiliation country: Pontificia Universidad Javeriana/CO

Full text: Available Collection: International databases Database: LILACS Main subject: Population Surveillance / Craniofacial Abnormalities / Hypospadias Type of study: Controlled clinical trial / Prevalence study / Risk factors / Screening study Limits: Humans / Male / Infant, Newborn Country/Region as subject: South America Language: English Journal: Int. braz. j. urol Journal subject: Urology Year: 2016 Document type: Article Affiliation country: Colombia Institution/Affiliation country: Pontificia Universidad Javeriana/CO
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