Gene transfer of dominant-negative RhoA increases outflow facility in perfused human anterior segment cultures.

Vittitow, Jason L; Garg, Rahul; Rowlette, Laura-Leigh S; Epstein, David L; O'Brien, Edward T; Borrás, Teresa

Vittitow, Jason L; Garg, Rahul; Rowlette, Laura-Leigh S; Epstein, David L; O'Brien, Edward T; Borrás, Teresa.

Affiliation

Vittitow JL; Dept. of Ophthalmology, Duke University Medical Center, Durham, NC 27710, USA. jason.vittitow@duke.edu

Mol Vis ; 8: 32-44, 2002 Mar 06.

Article in En | MEDLINE | ID: mdl-11889464

Subject(s)

Aqueous Humor/metabolism; Gene Expression Regulation/physiology; Trabecular Meshwork/metabolism; rhoA GTP-Binding Protein/genetics; Actins/metabolism; Adenoviridae/genetics; Aged; Aged, 80 and over; Blotting, Northern; Cytoskeletal Proteins/metabolism; Cytoskeleton/drug effects; Cytoskeleton/metabolism; Female; Gene Transfer Techniques; Genetic Vectors; Humans; Male; Membrane Proteins/metabolism; Organ Culture Techniques; Paxillin; Perfusion; Phosphoproteins/metabolism; Pressure; RNA, Messenger/metabolism; Trabecular Meshwork/drug effects; Zonula Occludens-1 Protein; rhoA GTP-Binding Protein/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Aqueous Humor / Trabecular Meshwork / Gene Expression Regulation / RhoA GTP-Binding Protein Limits: Aged / Aged80 / Female / Humans / Male Language: En Journal: Mol Vis Journal subject: BIOLOGIA MOLECULAR / OFTALMOLOGIA Year: 2002 Document type: Article Affiliation country: United States Country of publication: United States

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