Antibody blockade of Thy-1 (CD90) impairs mouse cytotoxic T lymphocyte induction by anti-CD3 monoclonal antibody.

Haeryfar, S M Mansour; Conrad, David M; Musgrave, Brucel; Hoskin, David W

Haeryfar, S M Mansour; Conrad, David M; Musgrave, Brucel; Hoskin, David W.

Affiliation

Haeryfar SM; Department of Microbiology and Immunology, Faculty of Medicine, Dalhousie University, Halifax, Canada.

Immunol Cell Biol ; 83(4): 352-63, 2005 Aug.

Article in En | MEDLINE | ID: mdl-16033530

Subject(s)

Antibodies, Monoclonal/immunology; CD3 Complex/immunology; T-Lymphocytes, Cytotoxic/immunology; Thy-1 Antigens/immunology; Animals; Antibodies, Monoclonal/pharmacology; Antigens, Differentiation/genetics; Cell Proliferation/drug effects; Endopeptidases/genetics; Gene Expression Regulation/drug effects; Granzymes; Interleukin-2/genetics; Interleukin-2/pharmacology; Membrane Proteins/genetics; Mice; Mice, Inbred C57BL; Pore Forming Cytotoxic Proteins; Protein Kinase C/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; Receptors, Interleukin-2/metabolism; T-Lymphocytes, Cytotoxic/cytology; T-Lymphocytes, Cytotoxic/drug effects; T-Lymphocytes, Cytotoxic/metabolism; Thy-1 Antigens/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Cytotoxic / CD3 Complex / Thy-1 Antigens / Antibodies, Monoclonal Limits: Animals Language: En Journal: Immunol Cell Biol Journal subject: ALERGIA E IMUNOLOGIA Year: 2005 Document type: Article Affiliation country: Canada Country of publication: United States

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