Enhancement of rat bladder contraction by artificial sweeteners via increased extracellular Ca2+ influx.

Dasgupta, Jaydip; Elliott, Ruth A; Doshani, Angie; Tincello, Douglas G

Dasgupta, Jaydip; Elliott, Ruth A; Doshani, Angie; Tincello, Douglas G.

Affiliation

Dasgupta J; University of Leicester, Prolapse and Incontinence Group, Reproductive Sciences Section, Department of Cancer Studies and Molecular Medicine, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester, LE2 7LX, UK.

Toxicol Appl Pharmacol ; 217(2): 216-24, 2006 Dec 01.

Article in En | MEDLINE | ID: mdl-17046038

Subject(s)

Calcium/metabolism; Muscle Contraction/drug effects; Muscle, Smooth/drug effects; Sweetening Agents/pharmacology; Urinary Bladder/drug effects; Adenosine Triphosphate/analogs & derivatives; Adenosine Triphosphate/pharmacology; Animals; Aspartame/pharmacology; Atropine/pharmacology; Calcium Channels, L-Type/drug effects; Calcium Channels, L-Type/metabolism; Carbachol/pharmacology; Cholinergic Agonists/pharmacology; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Muscarinic Antagonists/pharmacology; Muscle, Smooth/metabolism; Potassium Chloride/pharmacology; Rats; Rats, Wistar; Saccharin/pharmacology; Thiazines/pharmacology; Urinary Bladder/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Sweetening Agents / Urinary Bladder / Calcium / Muscle Contraction / Muscle, Smooth Type of study: Observational_studies / Risk_factors_studies Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2006 Document type: Article Affiliation country: United kingdom Country of publication: United States

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