An immunocompetent murine model for oncolysis with an armed and targeted measles virus.

Ungerechts, Guy; Springfeld, Christoph; Frenzke, Marie E; Lampe, Johanna; Parker, William B; Sorscher, Eric J; Cattaneo, Roberto

Ungerechts, Guy; Springfeld, Christoph; Frenzke, Marie E; Lampe, Johanna; Parker, William B; Sorscher, Eric J; Cattaneo, Roberto.

Affiliation

Ungerechts G; Molecular Medicine Program and Virology and Gene Therapy Track, Mayo Clinic College of Medicine, Rochester, Minnesota 55902, USA.

Mol Ther ; 15(11): 1991-7, 2007 Nov.

Article in En | MEDLINE | ID: mdl-17712331

Subject(s)

Colonic Neoplasms/immunology; Colonic Neoplasms/metabolism; Disease Models, Animal; Immunocompetence/immunology; Measles virus/immunology; Measles virus/metabolism; Animals; Bystander Effect; Cell Line; Chlorocebus aethiops; Colonic Neoplasms/genetics; Colonic Neoplasms/pathology; Cyclophosphamide/pharmacology; Gene Targeting; Genetic Therapy/adverse effects; Immunosuppression Therapy; Measles/genetics; Measles/immunology; Measles/metabolism; Measles/pathology; Measles virus/drug effects; Measles virus/genetics; Mice; Mice, Inbred C57BL; Prodrugs/therapeutic use; Prodrugs/toxicity; Survival Rate

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Collection: 01-internacional Database: MEDLINE Main subject: Colonic Neoplasms / Disease Models, Animal / Immunocompetence / Measles virus Limits: Animals Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2007 Document type: Article Affiliation country: United States Country of publication: United States

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