APOE genotype-specific differences in the innate immune response.

Vitek, Michael P; Brown, Candice M; Colton, Carol A

Vitek, Michael P; Brown, Candice M; Colton, Carol A.

Affiliation

Vitek MP; Duke University Medical Center, Durham, NC 27710, USA. mikevitek@cognosci.com

Neurobiol Aging ; 30(9): 1350-60, 2009 Sep.

Article in En | MEDLINE | ID: mdl-18155324

Subject(s)

Apolipoproteins E/genetics; Encephalitis/genetics; Encephalitis/immunology; Immunity, Innate/genetics; Microglia/immunology; Animals; Animals, Newborn; Apolipoprotein E3/genetics; Apolipoprotein E3/metabolism; Apolipoprotein E4/genetics; Apolipoprotein E4/metabolism; Apolipoproteins E/metabolism; Cells, Cultured; Cerebral Cortex/immunology; Cerebral Cortex/pathology; Cerebral Cortex/physiopathology; Cytokines/metabolism; Gene Dosage/genetics; Genotype; Humans; Mice; Mice, Knockout; Mice, Transgenic; Microglia/drug effects; Microglia/metabolism; Nitric Oxide Synthase Type II/genetics; RNA, Messenger/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Microglia / Encephalitis / Immunity, Innate Limits: Animals / Humans Language: En Journal: Neurobiol Aging Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States

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