Methylenetetrahydrofolate reductase gene, homocysteine and coronary artery disease: the A1298C polymorphism does matter. Inferences from a case study (Madeira, Portugal).

Freitas, Ana I; Mendonça, Isabel; Guerra, Graça; Brión, Maria; Reis, Roberto P; Carracedo, Angel; Brehm, António

Freitas, Ana I; Mendonça, Isabel; Guerra, Graça; Brión, Maria; Reis, Roberto P; Carracedo, Angel; Brehm, António.

Affiliation

Freitas AI; Human Genetics Laboratory, University of Madeira, Funchal, Portugal.

Thromb Res ; 122(5): 648-56, 2008.

Article in En | MEDLINE | ID: mdl-18384842

Subject(s)

Coronary Artery Disease/blood; Coronary Artery Disease/genetics; Homocysteine/blood; Methylenetetrahydrofolate Reductase (NADPH2)/genetics; Polymorphism, Single Nucleotide; Adult; Aged; Alleles; Case-Control Studies; Coronary Artery Disease/enzymology; Coronary Artery Disease/etiology; Female; Gene Frequency; Genotype; Haplotypes; Humans; Hyperhomocysteinemia/complications; Hyperhomocysteinemia/enzymology; Hyperhomocysteinemia/genetics; Male; Middle Aged; Portugal; Risk Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Coronary Artery Disease / Polymorphism, Single Nucleotide / Methylenetetrahydrofolate Reductase (NADPH2) / Homocysteine Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Thromb Res Year: 2008 Document type: Article Affiliation country: Portugal Country of publication: United States

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