Human parainfluenza virus type 2 V protein inhibits interferon production and signaling and is required for replication in non-human primates.

Schaap-Nutt, Anne; D'Angelo, Christopher; Scull, Margaret A; Amaro-Carambot, Emerito; Nishio, Machiko; Pickles, Raymond J; Collins, Peter L; Murphy, Brian R; Schmidt, Alexander C

Schaap-Nutt, Anne; D'Angelo, Christopher; Scull, Margaret A; Amaro-Carambot, Emerito; Nishio, Machiko; Pickles, Raymond J; Collins, Peter L; Murphy, Brian R; Schmidt, Alexander C.

Affiliation

Schaap-Nutt A; Laboratory of Infectious Diseases, RNA Viruses Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA. schaapa@niaid.nih.gov

Virology ; 397(2): 285-98, 2010 Feb 20.

Article in En | MEDLINE | ID: mdl-19969320

Subject(s)

Interferons/immunology; Parainfluenza Virus 2, Human/immunology; Parainfluenza Virus 2, Human/physiology; Signal Transduction; Viral Proteins/immunology; Viral Proteins/physiology; Virus Replication; Animals; Cells, Cultured; Chlorocebus aethiops; Down-Regulation; Gene Knockout Techniques; Humans; Monkey Diseases/pathology; Monkey Diseases/virology; Parainfluenza Virus 2, Human/genetics; Respiratory Tract Infections/pathology; Respiratory Tract Infections/virology; Viral Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Virus Replication / Signal Transduction / Interferons / Parainfluenza Virus 2, Human Limits: Animals / Humans Language: En Journal: Virology Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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