Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity.

Noble, Suzanne M; French, Sarah; Kohn, Lisa A; Chen, Victoria; Johnson, Alexander D

Noble, Suzanne M; French, Sarah; Kohn, Lisa A; Chen, Victoria; Johnson, Alexander D.

Affiliation

Noble SM; Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California, USA. suzanne.noble@ucsf.edu

Nat Genet ; 42(7): 590-8, 2010 Jul.

Article in En | MEDLINE | ID: mdl-20543849

Subject(s)

Candida albicans/genetics; Candidiasis/microbiology; Gene Deletion; Gene Library; Animals; Candida albicans/growth & development; Candida albicans/pathogenicity; Female; Fungal Proteins/genetics; Fungal Proteins/metabolism; Glucosylceramides/biosynthesis; Glucosylceramides/chemistry; Homozygote; Humans; Hyphae/genetics; Hyphae/growth & development; Hyphae/metabolism; Mice; Mice, Inbred BALB C; Molecular Structure; Morphogenesis; Mutation; Survival Analysis; Virulence/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida albicans / Candidiasis / Gene Library / Gene Deletion Limits: Animals / Female / Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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