The adaptor protein AMOT promotes the proliferation of mammary epithelial cells via the prolonged activation of the extracellular signal-regulated kinases.

Ranahan, William P; Han, Zhang; Smith-Kinnaman, Whitney; Nabinger, Sarah C; Heller, Brigitte; Herbert, Britney-Shea; Chan, Rebecca; Wells, Clark D

Ranahan, William P; Han, Zhang; Smith-Kinnaman, Whitney; Nabinger, Sarah C; Heller, Brigitte; Herbert, Britney-Shea; Chan, Rebecca; Wells, Clark D.

Affiliation

Ranahan WP; Department of Biochemistry and Molecular Biology, University of Indiana School of Medicine, Indianapolis, Indiana 46202-5122, USA.

Cancer Res ; 71(6): 2203-11, 2011 Mar 15.

Article in En | MEDLINE | ID: mdl-21285250

Subject(s)

Cell Proliferation; Epithelial Cells/metabolism; Extracellular Signal-Regulated MAP Kinases/metabolism; Intercellular Signaling Peptides and Proteins/metabolism; Membrane Proteins/metabolism; Angiomotins; Cell Line; Cell Line, Tumor; Collagen; Drug Combinations; Enzyme Activation; Epithelial Cells/cytology; Female; HEK293 Cells; Humans; Immunoblotting; Intercellular Signaling Peptides and Proteins/genetics; Laminin; Luminescent Proteins/genetics; Luminescent Proteins/metabolism; Mammary Glands, Human/cytology; Membrane Proteins/genetics; Microfilament Proteins; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinase 3/metabolism; Mutation; Proteoglycans; RNA Interference; Signal Transduction; Time Factors; Tumor Microenvironment

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Intercellular Signaling Peptides and Proteins / Extracellular Signal-Regulated MAP Kinases / Cell Proliferation / Epithelial Cells / Membrane Proteins Limits: Female / Humans Language: En Journal: Cancer Res Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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