Insulin-induced oxidative stress up-regulates heme oxygenase-1 via diverse signaling cascades in the C2 skeletal myoblast cell line.

Aggeli, Ioanna-Katerina; Theofilatos, Dimitris; Beis, Isidoros; Gaitanaki, Catherine

Aggeli, Ioanna-Katerina; Theofilatos, Dimitris; Beis, Isidoros; Gaitanaki, Catherine.

Affiliation

Aggeli IK; Department of Animal and Human Physiology, School of Biology, University of Athens, Panepistimioupolis, Ilissia, Athens 157 84 Greece.

Endocrinology ; 152(4): 1274-83, 2011 Apr.

Article in En | MEDLINE | ID: mdl-21325398

Subject(s)

Heme Oxygenase-1/metabolism; Insulin/pharmacology; Myoblasts, Skeletal/metabolism; Oxidative Stress/drug effects; Animals; Anthracenes/pharmacology; Antioxidants/pharmacology; Ascorbic Acid/pharmacology; Blotting, Western; Caspase 3/metabolism; Catalase/pharmacology; Cell Line; Cell Survival/drug effects; Enzyme Activation/drug effects; Enzyme Inhibitors/pharmacology; Flavonoids/pharmacology; Heme Oxygenase-1/antagonists & inhibitors; JNK Mitogen-Activated Protein Kinases/antagonists & inhibitors; JNK Mitogen-Activated Protein Kinases/metabolism; Mice; Mitogen-Activated Protein Kinase 1/antagonists & inhibitors; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinase 3/antagonists & inhibitors; Mitogen-Activated Protein Kinase 3/metabolism; Myoblasts, Skeletal/drug effects; Myoblasts, Skeletal/enzymology; NF-kappa B/metabolism; Phosphorylation/drug effects; Protoporphyrins/pharmacology; Reactive Oxygen Species/metabolism; Signal Transduction/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Stress / Myoblasts, Skeletal / Heme Oxygenase-1 / Insulin Limits: Animals Language: En Journal: Endocrinology Year: 2011 Document type: Article Country of publication: United States

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