Iron accumulation and neurotoxicity in cortical cultures treated with holotransferrin.

Chen-Roetling, Jing; Liu, Wenpei; Regan, Raymond F

Chen-Roetling, Jing; Liu, Wenpei; Regan, Raymond F.

Affiliation

Chen-Roetling J; Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA

Free Radic Biol Med ; 51(11): 1966-74, 2011 Dec 01.

Article in En | MEDLINE | ID: mdl-21939754

Subject(s)

Iron/metabolism; Iron/toxicity; Neurons/drug effects; Transferrin/pharmacology; Animals; Antioxidants/pharmacology; Cation Transport Proteins/biosynthesis; Cells, Cultured; Dose-Response Relationship, Drug; Ferritins/biosynthesis; Heme Oxygenase-1/biosynthesis; Humans; Iron/blood; Iron Chelating Agents/pharmacology; Mice; Neurons/cytology; Neurons/metabolism; Receptors, Transferrin/biosynthesis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transferrin / Iron / Neurons Limits: Animals / Humans Language: En Journal: Free Radic Biol Med Journal subject: BIOQUIMICA / MEDICINA Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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