CYP5122A1, a novel cytochrome P450 is essential for survival of Leishmania donovani.

Verma, Smriti; Mehta, Ashish; Shaha, Chandrima

Verma, Smriti; Mehta, Ashish; Shaha, Chandrima.

Affiliation

Verma S; Cell Death and Differentiation Research Laboratory, Centre for Molecular Medicine National Institute of Immunology, New Delhi, India.

PLoS One ; 6(9): e25273, 2011.

Article in En | MEDLINE | ID: mdl-21966477

Subject(s)

Cytochrome P-450 Enzyme System/metabolism; Leishmania donovani/metabolism; Leishmania donovani/pathogenicity; Protozoan Proteins/metabolism; Adenosine Triphosphate/metabolism; Animals; Blotting, Western; Cricetinae; Cytochrome P-450 Enzyme System/classification; Cytochrome P-450 Enzyme System/genetics; Electrophoresis, Polyacrylamide Gel; Ergosterol/metabolism; Genome, Protozoan/genetics; Immunohistochemistry; Leishmania donovani/genetics; Leishmaniasis, Visceral/parasitology; Mesocricetus; Mitochondria/drug effects; Mitochondria/metabolism; Phylogeny; Protozoan Proteins/classification; Protozoan Proteins/genetics; Reactive Oxygen Species/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leishmania donovani / Protozoan Proteins / Cytochrome P-450 Enzyme System Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2011 Document type: Article Affiliation country: India Country of publication: United States

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