Infectivity in chimpanzees (Pan troglodytes) of plasma collected before HCV RNA detectability by FDA-licensed assays: implications for transfusion safety and HCV infection outcomes.

Busch, Michael P; Murthy, Krishna K; Kleinman, Steven H; Hirschkorn, Dale F; Herring, Belinda L; Delwart, Eric L; Racanelli, Vito; Yoon, Joo Chun; Rehermann, Barbara; Alter, Harvey J

Busch, Michael P; Murthy, Krishna K; Kleinman, Steven H; Hirschkorn, Dale F; Herring, Belinda L; Delwart, Eric L; Racanelli, Vito; Yoon, Joo Chun; Rehermann, Barbara; Alter, Harvey J.

Affiliation

Busch MP; Blood Systems Research Institute, San Francisco, CA 94118, USA. mbusch@bloodsystems.org

Blood ; 119(26): 6326-34, 2012 Jun 28.

Article in En | MEDLINE | ID: mdl-22498743

Subject(s)

Blood Donors; Blood Safety/methods; Hepacivirus/genetics; Hepatitis C/blood; Hepatitis C/transmission; RNA, Viral/blood; Animals; Blood Donors/legislation & jurisprudence; Blood Safety/standards; Blood Specimen Collection; Blood-Borne Pathogens/isolation & purification; Female; Hepacivirus/isolation & purification; Hepatitis C/diagnosis; Hepatitis C/virology; Licensure; Limit of Detection; Pan troglodytes; RNA, Viral/analysis; RNA, Viral/isolation & purification; Serologic Tests/methods; United States; United States Food and Drug Administration/legislation & jurisprudence

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Donors / RNA, Viral / Hepatitis C / Hepacivirus / Blood Safety Type of study: Diagnostic_studies / Evaluation_studies / Prognostic_studies Limits: Animals Country/Region as subject: America do norte Language: En Journal: Blood Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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