Pomegranate phytoconstituents blunt the inflammatory cascade in a chemically induced rodent model of hepatocellular carcinogenesis.

Bishayee, Anupam; Thoppil, Roslin J; Darvesh, Altaf S; Ohanyan, Vahagn; Meszaros, J Gary; Bhatia, Deepak

Bishayee, Anupam; Thoppil, Roslin J; Darvesh, Altaf S; Ohanyan, Vahagn; Meszaros, J Gary; Bhatia, Deepak.

Affiliation

Bishayee A; Department of Pharmaceutical Sciences, School of Pharmacy, American University of Health Sciences, Signal Hill, CA 90755, USA. abishayee@auhs.edu

J Nutr Biochem ; 24(1): 178-87, 2013 Jan.

Article in En | MEDLINE | ID: mdl-22841394

Subject(s)

Carcinoma, Hepatocellular/drug therapy; Inflammation/drug therapy; Liver Neoplasms/drug therapy; Lythraceae/chemistry; Plant Extracts/pharmacology; Animals; Anticarcinogenic Agents/pharmacology; Carcinoma, Hepatocellular/chemically induced; Carcinoma, Hepatocellular/metabolism; Cyclooxygenase 2/metabolism; Diethylnitrosamine/toxicity; Echocardiography; HSP70 Heat-Shock Proteins/metabolism; HSP90 Heat-Shock Proteins/metabolism; Heart/physiology; Inflammation/metabolism; Liver/drug effects; Liver/metabolism; Liver Neoplasms/chemically induced; Liver Neoplasms/metabolism; Liver Neoplasms, Experimental/chemically induced; Liver Neoplasms, Experimental/drug therapy; Liver Neoplasms, Experimental/metabolism; Male; NF-kappa B/genetics; NF-kappa B/metabolism; Nitric Oxide Synthase Type II/metabolism; Rats; Rats, Sprague-Dawley; Tyrosine/analogs & derivatives; Tyrosine/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Carcinoma, Hepatocellular / Lythraceae / Inflammation / Liver Neoplasms Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Nutr Biochem Journal subject: BIOQUIMICA / CIENCIAS DA NUTRICAO Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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