[6]-Gingerol induces bone loss in ovary intact adult mice and augments osteoclast function via the transient receptor potential vanilloid 1 channel.

Khan, Kainat; Singh, Akanksha; Mittal, Monika; Sharan, Kunal; Singh, Nidhi; Dixit, Preety; Sanyal, Sabyasachi; Maurya, Rakesh; Chattopadhyay, Naibedya

Khan, Kainat; Singh, Akanksha; Mittal, Monika; Sharan, Kunal; Singh, Nidhi; Dixit, Preety; Sanyal, Sabyasachi; Maurya, Rakesh; Chattopadhyay, Naibedya.

Affiliation

Khan K; Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, India.

Mol Nutr Food Res ; 56(12): 1860-73, 2012 Dec.

Article in En | MEDLINE | ID: mdl-23034900

Subject(s)

Bone Diseases, Metabolic/chemically induced; Catechols/adverse effects; Fatty Alcohols/adverse effects; Osteoclasts/drug effects; Plant Extracts/adverse effects; TRPV Cation Channels/metabolism; Administration, Oral; Alkaline Phosphatase/analysis; Alkaline Phosphatase/metabolism; Animals; Bone Diseases, Metabolic/pathology; Calcium/metabolism; Capsaicin/pharmacology; Cell Differentiation; Cell Survival; Female; Genetic Markers; Zingiber officinale/chemistry; Mice; Mice, Inbred BALB C; Osteoblasts/drug effects; Osteoblasts/metabolism; Osteoclasts/cytology; Ovariectomy/methods; Ovary/drug effects; Real-Time Polymerase Chain Reaction; TRPV Cation Channels/genetics

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoclasts / Bone Diseases, Metabolic / Plant Extracts / Catechols / TRPV Cation Channels / Fatty Alcohols Limits: Animals Language: En Journal: Mol Nutr Food Res Journal subject: CIENCIAS DA NUTRICAO Year: 2012 Document type: Article Affiliation country: India Country of publication: Germany

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google