Chemovirotherapy of malignant melanoma with a targeted and armed oncolytic measles virus.

Kaufmann, Johanna K; Bossow, Sascha; Grossardt, Christian; Sawall, Stefanie; Kupsch, Jörg; Erbs, Philippe; Hassel, Jessica C; von Kalle, Christof; Enk, Alexander H; Nettelbeck, Dirk M; Ungerechts, Guy

Kaufmann, Johanna K; Bossow, Sascha; Grossardt, Christian; Sawall, Stefanie; Kupsch, Jörg; Erbs, Philippe; Hassel, Jessica C; von Kalle, Christof; Enk, Alexander H; Nettelbeck, Dirk M; Ungerechts, Guy.

Affiliation

Kaufmann JK; Helmholtz University Group Oncolytic Adenoviruses, German Cancer Research Center, Heidelberg, Germany.

J Invest Dermatol ; 133(4): 1034-42, 2013 Apr.

Article in En | MEDLINE | ID: mdl-23223133

Subject(s)

Measles virus/genetics; Melanoma/drug therapy; Oncolytic Virotherapy/methods; Prodrugs/pharmacokinetics; Skin Neoplasms/drug therapy; Animals; Antigens, Neoplasm/metabolism; Antimetabolites/metabolism; Biopsy; Cell Line, Tumor; Chlorocebus aethiops; Combined Modality Therapy; Female; Flucytosine/metabolism; Genetic Engineering/methods; Genome, Viral/genetics; Humans; Melanoma/secondary; Mice; Mice, Inbred NOD; Mice, SCID; Recombinant Proteins/genetics; Skin Neoplasms/pathology; Vero Cells; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Prodrugs / Oncolytic Virotherapy / Measles virus / Melanoma Limits: Animals / Female / Humans Language: En Journal: J Invest Dermatol Year: 2013 Document type: Article Affiliation country: Germany Country of publication: United States

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