Inhibition of mycobacterial alanine racemase activity and growth by thiadiazolidinones.

Lee, Yashang; Mootien, Sara; Shoen, Carolyn; Destefano, Michelle; Cirillo, Pier; Asojo, Oluwatoyin A; Yeung, Kacheong R; Ledizet, Michel; Cynamon, Michael H; Aristoff, Paul A; Koski, Raymond A; Kaplan, Paul A; Anthony, Karen G

Lee, Yashang; Mootien, Sara; Shoen, Carolyn; Destefano, Michelle; Cirillo, Pier; Asojo, Oluwatoyin A; Yeung, Kacheong R; Ledizet, Michel; Cynamon, Michael H; Aristoff, Paul A; Koski, Raymond A; Kaplan, Paul A; Anthony, Karen G.

Affiliation

Lee Y; L2 Diagnostics LLC, 300 George St., New Haven, CT 06511, USA.

Biochem Pharmacol ; 86(2): 222-30, 2013 Jul 15.

Article in En | MEDLINE | ID: mdl-23680030

Subject(s)

Alanine Racemase/antagonists & inhibitors; Mycobacterium smegmatis/drug effects; Mycobacterium tuberculosis/drug effects; Thiadiazoles/pharmacology; Alanine Racemase/chemistry; Alanine Racemase/metabolism; Amino Acid Sequence; Catalysis; Molecular Sequence Data; Mycobacterium smegmatis/enzymology; Mycobacterium tuberculosis/enzymology; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiadiazoles / Mycobacterium smegmatis / Alanine Racemase / Mycobacterium tuberculosis Language: En Journal: Biochem Pharmacol Year: 2013 Document type: Article Affiliation country: United States Country of publication: United kingdom

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