Dengue virus photo-inactivated in presence of 1,5-iodonaphthylazide (INA) or AMT, a psoralen compound (4'-aminomethyl-trioxsalen) is highly immunogenic in mice.

Raviprakash, Kanakatte; Sun, Peifang; Raviv, Yossef; Luke, Thomas; Martin, Nicholas; Kochel, Tadeusz

Raviprakash, Kanakatte; Sun, Peifang; Raviv, Yossef; Luke, Thomas; Martin, Nicholas; Kochel, Tadeusz.

Affiliation

Raviprakash K; Viral & Rickettsial Diseases Department; Naval Medical Research Center; Silver Spring, MD USA.

Hum Vaccin Immunother ; 9(11): 2336-41, 2013 Nov.

Article in En | MEDLINE | ID: mdl-23835446

Subject(s)

Azides/pharmacology; Dengue Vaccines/immunology; Dengue Virus/drug effects; Dengue Virus/immunology; Disinfectants/pharmacology; Trioxsalen/analogs & derivatives; Virus Inactivation; Animals; Antibodies, Neutralizing/blood; Antibodies, Viral/blood; Dengue Vaccines/administration & dosage; Formaldehyde/pharmacology; Light; Mice, Inbred BALB C; T-Lymphocytes/immunology; Trioxsalen/pharmacology; Vaccines, Inactivated/administration & dosage; Vaccines, Inactivated/immunology

Key words

dengue virus; immunogenicity; mouse; vaccine; virus inactivation

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azides / Trioxsalen / Dengue Virus / Virus Inactivation / Disinfectants / Dengue Vaccines Limits: Animals Language: En Journal: Hum Vaccin Immunother Year: 2013 Document type: Article Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google