Universal anti-neuraminidase antibody inhibiting all influenza A subtypes.

Doyle, Tracey M; Hashem, Anwar M; Li, Changgui; Van Domselaar, Gary; Larocque, Louise; Wang, Junzhi; Smith, Daryl; Cyr, Terry; Farnsworth, Aaron; He, Runtao; Hurt, Aeron C; Brown, Earl G; Li, Xuguang

Doyle, Tracey M; Hashem, Anwar M; Li, Changgui; Van Domselaar, Gary; Larocque, Louise; Wang, Junzhi; Smith, Daryl; Cyr, Terry; Farnsworth, Aaron; He, Runtao; Hurt, Aeron C; Brown, Earl G; Li, Xuguang.

Affiliation

Doyle TM; Centre for Vaccine Evaluation, Biologics and Genetic Therapies Directorate, HPFB, Health Canada, Ottawa, ON, Canada; Department of Biochemistry, Microbiology and Immunology and Emerging Pathogens Research Centre, University of Ottawa, Ottawa, ON, Canada.

Antiviral Res ; 100(2): 567-74, 2013 Nov.

Article in En | MEDLINE | ID: mdl-24091204

Subject(s)

Antibodies, Monoclonal/immunology; Antibodies, Viral/immunology; Cross Protection; Influenza A Virus, H1N1 Subtype/immunology; Influenza A Virus, H3N2 Subtype/immunology; Neuraminidase/immunology; Orthomyxoviridae Infections/prevention & control; Viral Proteins/immunology; Animals; Antibodies, Monoclonal/isolation & purification; Antibodies, Viral/isolation & purification; Disease Models, Animal; Epitopes, B-Lymphocyte/immunology; Female; Mice; Orthomyxoviridae Infections/immunology; Orthomyxoviridae Infections/virology

Key words

Cross-protection; Neuraminidase; Universal antibody

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Orthomyxoviridae Infections / Influenza A Virus, H1N1 Subtype / Influenza A Virus, H3N2 Subtype / Cross Protection / Antibodies, Monoclonal / Antibodies, Viral / Neuraminidase Limits: Animals Language: En Journal: Antiviral Res Year: 2013 Document type: Article Affiliation country: Canada Country of publication: Netherlands

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