A novel strategy to develop a robust infectious hepatitis C virus cell culture system directly from a clinical isolate.

Lu, Jie; Xiang, Yu; Tao, Wanyin; Li, Qingchao; Wang, Na; Gao, Yongfeng; Xiang, Xiaogang; Xie, Qing; Zhong, Jin

Lu, Jie; Xiang, Yu; Tao, Wanyin; Li, Qingchao; Wang, Na; Gao, Yongfeng; Xiang, Xiaogang; Xie, Qing; Zhong, Jin.

Affiliation

Lu J; Unit of Viral Hepatitis, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

J Virol ; 88(3): 1484-91, 2014 Feb.

Article in En | MEDLINE | ID: mdl-24227861

Subject(s)

Cell Culture Techniques/methods; Genetic Engineering/methods; Hepacivirus/physiology; Hepatitis C/virology; Virus Replication; Cell Line, Tumor; DNA, Complementary/genetics; DNA, Complementary/metabolism; Hepacivirus/classification; Hepacivirus/genetics; Hepacivirus/isolation & purification; Humans; Molecular Sequence Data; Mutation; Phylogeny; RNA, Viral/genetics; RNA, Viral/metabolism; Viral Proteins/genetics; Viral Proteins/metabolism; Virus Cultivation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Virus Replication / Genetic Engineering / Hepatitis C / Hepacivirus / Cell Culture Techniques Type of study: Evaluation_studies Limits: Humans Language: En Journal: J Virol Year: 2014 Document type: Article Affiliation country: China Country of publication: United States

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