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A highly conserved Toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage.
Cavailles, Pierre; Flori, Pierre; Papapietro, Olivier; Bisanz, Cordelia; Lagrange, Dominique; Pilloux, Ludovic; Massera, Céline; Cristinelli, Sara; Jublot, Delphine; Bastien, Olivier; Loeuillet, Corinne; Aldebert, Delphine; Touquet, Bastien; Fournié, Gilbert J; Cesbron-Delauw, Marie France.
Affiliation
  • Cavailles P; UMR 5163, Centre National de la Recherche Scientifique (CNRS), Grenoble, France; Université Grenoble 1, Grenoble, France.
  • Flori P; UMR 5163, Centre National de la Recherche Scientifique (CNRS), Grenoble, France; GIMAP, EA 3064, Saint-Etienne, France.
  • Papapietro O; UMR Inserm, U1043, Toulouse, France; Université de Toulouse, UPS, Centre de Physiopathologie de Toulouse Purpan (CPTP), Toulouse, France.
  • Bisanz C; UMR 5163, Centre National de la Recherche Scientifique (CNRS), Grenoble, France; Université Grenoble 1, Grenoble, France.
  • Lagrange D; UMR Inserm, U1043, Toulouse, France; Université de Toulouse, UPS, Centre de Physiopathologie de Toulouse Purpan (CPTP), Toulouse, France.
  • Pilloux L; UMR 5163, Centre National de la Recherche Scientifique (CNRS), Grenoble, France; Université Grenoble 1, Grenoble, France.
  • Massera C; UMR 5163, Centre National de la Recherche Scientifique (CNRS), Grenoble, France; Université Grenoble 1, Grenoble, France.
  • Cristinelli S; UMR 5163, Centre National de la Recherche Scientifique (CNRS), Grenoble, France; Université Grenoble 1, Grenoble, France.
  • Jublot D; UMR 5163, Centre National de la Recherche Scientifique (CNRS), Grenoble, France; Université Grenoble 1, Grenoble, France.
  • Bastien O; UMR 5168, CNRS/INRA, Université Joseph Fourier, CEA, Grenoble, France.
  • Loeuillet C; UMR 5163, Centre National de la Recherche Scientifique (CNRS), Grenoble, France; Université Grenoble 1, Grenoble, France.
  • Aldebert D; UMR 5163, Centre National de la Recherche Scientifique (CNRS), Grenoble, France; Université Grenoble 1, Grenoble, France.
  • Touquet B; UMR 5163, Centre National de la Recherche Scientifique (CNRS), Grenoble, France; Université Grenoble 1, Grenoble, France.
  • Fournié GJ; UMR Inserm, U1043, Toulouse, France; Université de Toulouse, UPS, Centre de Physiopathologie de Toulouse Purpan (CPTP), Toulouse, France.
  • Cesbron-Delauw MF; UMR 5163, Centre National de la Recherche Scientifique (CNRS), Grenoble, France; Université Grenoble 1, Grenoble, France.
PLoS Pathog ; 10(4): e1004005, 2014 Apr.
Article in En | MEDLINE | ID: mdl-24699513
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Toxoplasma / Haplotypes / Toxoplasmosis / Macrophages, Peritoneal / Caspase 1 / Adaptor Proteins, Signal Transducing / Apoptosis Regulatory Proteins / Genetic Loci Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: PLoS Pathog Year: 2014 Document type: Article Affiliation country: France Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Toxoplasma / Haplotypes / Toxoplasmosis / Macrophages, Peritoneal / Caspase 1 / Adaptor Proteins, Signal Transducing / Apoptosis Regulatory Proteins / Genetic Loci Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: PLoS Pathog Year: 2014 Document type: Article Affiliation country: France Country of publication: United States