Chronic diclofenac (DCF) exposure alters both enzymatic and haematological profile of African catfish, Clarias gariepinus.

Ajima, Malachy N O; Ogo, Ogo A; Audu, Bala S; Ugwoegbu, Kyrian C

Ajima, Malachy N O; Ogo, Ogo A; Audu, Bala S; Ugwoegbu, Kyrian C.

Affiliation

Ajima MN; a Department of Fisheries and Aquaculture Technology , Federal University of Technology , Owerri , Nigeria .
Ogo OA; b Department of Biochemistry , Benue State University , Makurdi , Nigeria , and.
Audu BS; c Department of Zoology , University of Jos , Jos , Nigeria.
Ugwoegbu KC; a Department of Fisheries and Aquaculture Technology , Federal University of Technology , Owerri , Nigeria .

Drug Chem Toxicol ; 38(4): 383-90, 2015 Oct.

Article in En | MEDLINE | ID: mdl-25367777

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/toxicity; Catfishes/physiology; Diclofenac/toxicity; Water Pollutants, Chemical/toxicity; Alanine Transaminase/metabolism; Animals; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage; Aspartate Aminotransferases/metabolism; Catfishes/blood; Diclofenac/administration & dosage; Erythrocytes/drug effects; Female; Gills/drug effects; Glucose/metabolism; Hematocrit; L-Lactate Dehydrogenase/metabolism; Lethal Dose 50; Male; Toxicity Tests, Acute; Toxicity Tests, Chronic; Water Pollutants, Chemical/administration & dosage

Key words

Acute; Clarias gariepinus; chronic; enzymes; haematology; pharmaceuticals; toxicity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Water Pollutants, Chemical / Catfishes / Anti-Inflammatory Agents, Non-Steroidal / Diclofenac Limits: Animals Language: En Journal: Drug Chem Toxicol Year: 2015 Document type: Article Affiliation country: Nigeria Country of publication: United States

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