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A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment.
Spreafico, Roberto; Rossetti, Maura; van Loosdregt, Jorg; Wallace, Carol A; Massa, Margherita; Magni-Manzoni, Silvia; Gattorno, Marco; Martini, Alberto; Lovell, Daniel J; Albani, Salvatore.
Affiliation
  • Spreafico R; Translational Research Unit, Sanford-Burnham Medical Research Institute, San Diego, California, USA SingHealth Translational Immunology and Inflammation Centre, Singhealth and Duke-NUS Graduate Medical School, Singapore, Singapore.
  • Rossetti M; Translational Research Unit, Sanford-Burnham Medical Research Institute, San Diego, California, USA SingHealth Translational Immunology and Inflammation Centre, Singhealth and Duke-NUS Graduate Medical School, Singapore, Singapore.
  • van Loosdregt J; Translational Research Unit, Sanford-Burnham Medical Research Institute, San Diego, California, USA.
  • Wallace CA; Seattle Children's Hospital and Research Institute, Seattle, Washington, USA.
  • Massa M; Lab Biotecnologie, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
  • Magni-Manzoni S; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy.
  • Gattorno M; Second Pediatrics Division, University of Genoa and G Gaslini Institute, Genova, Italy.
  • Martini A; Second Pediatrics Division, University of Genoa and G Gaslini Institute, Genova, Italy.
  • Lovell DJ; Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Albani S; Translational Research Unit, Sanford-Burnham Medical Research Institute, San Diego, California, USA SingHealth Translational Immunology and Inflammation Centre, Singhealth and Duke-NUS Graduate Medical School, Singapore, Singapore.
Ann Rheum Dis ; 75(2): 459-65, 2016 Feb.
Article in En | MEDLINE | ID: mdl-25498120
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Juvenile / Synovial Membrane / CD4-Positive T-Lymphocytes / Genes, T-Cell Receptor beta Type of study: Prognostic_studies Limits: Humans Language: En Journal: Ann Rheum Dis Year: 2016 Document type: Article Affiliation country: Singapore Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Juvenile / Synovial Membrane / CD4-Positive T-Lymphocytes / Genes, T-Cell Receptor beta Type of study: Prognostic_studies Limits: Humans Language: En Journal: Ann Rheum Dis Year: 2016 Document type: Article Affiliation country: Singapore Country of publication: United kingdom