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A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity.
Johansen, Lisa M; DeWald, Lisa Evans; Shoemaker, Charles J; Hoffstrom, Benjamin G; Lear-Rooney, Calli M; Stossel, Andrea; Nelson, Elizabeth; Delos, Sue E; Simmons, James A; Grenier, Jill M; Pierce, Laura T; Pajouhesh, Hassan; Lehár, Joseph; Hensley, Lisa E; Glass, Pamela J; White, Judith M; Olinger, Gene G.
Affiliation
  • Johansen LM; Horizon Discovery Inc., 245 First Street, Cambridge, MA 02142, USA.
  • DeWald LE; U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
  • Shoemaker CJ; University of Virginia, 1340 Jefferson Park Avenue, Charlottesville, VA 22908, USA.
  • Hoffstrom BG; Horizon Discovery Inc., 245 First Street, Cambridge, MA 02142, USA.
  • Lear-Rooney CM; U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
  • Stossel A; U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
  • Nelson E; University of Virginia, 1340 Jefferson Park Avenue, Charlottesville, VA 22908, USA.
  • Delos SE; University of Virginia, 1340 Jefferson Park Avenue, Charlottesville, VA 22908, USA.
  • Simmons JA; University of Virginia, 1340 Jefferson Park Avenue, Charlottesville, VA 22908, USA.
  • Grenier JM; Horizon Discovery Inc., 245 First Street, Cambridge, MA 02142, USA.
  • Pierce LT; Horizon Discovery Inc., 245 First Street, Cambridge, MA 02142, USA.
  • Pajouhesh H; Horizon Discovery Inc., 245 First Street, Cambridge, MA 02142, USA.
  • Lehár J; Horizon Discovery Inc., 245 First Street, Cambridge, MA 02142, USA. Bioinformatics Program, Boston University, 20 Cummington Street, Boston, MA 02215, USA.
  • Hensley LE; U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
  • Glass PJ; U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
  • White JM; University of Virginia, 1340 Jefferson Park Avenue, Charlottesville, VA 22908, USA.
  • Olinger GG; U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA. gene.olinger@nih.gov.
Sci Transl Med ; 7(290): 290ra89, 2015 Jun 03.
Article in En | MEDLINE | ID: mdl-26041706

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Molecular Probes / Drug Approval / Hemorrhagic Fever, Ebola Limits: Animals / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2015 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Molecular Probes / Drug Approval / Hemorrhagic Fever, Ebola Limits: Animals / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2015 Document type: Article Affiliation country: United States Country of publication: United States