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Intranasal vaccination of recombinant H5N1 HA1 proteins fused with foldon and Fc induces strong mucosal immune responses with neutralizing activity: Implication for developing novel mucosal influenza vaccines.
Yu, Fei; Li, Ye; Guo, Yan; Wang, Lili; Yang, Jie; Zhao, Guangyu; Zhou, Yusen; Du, Lanying; Jiang, Shibo.
Affiliation
  • Yu F; a Lindsley F. Kimball Research Institute; New York Blood Center ; New York , NY USA.
  • Li Y; b Key Laboratory of Medical Molecular Virology of Ministries of Education and Health; Shanghai Medical College and Institute of Medical Microbiology; Fudan University ; Shanghai , China.
  • Guo Y; a Lindsley F. Kimball Research Institute; New York Blood Center ; New York , NY USA.
  • Wang L; c State Key Laboratory of Pathogen and Biosecurity; Beijing Institute of Microbiology and Epidemiology ; Beijing , China.
  • Yang J; a Lindsley F. Kimball Research Institute; New York Blood Center ; New York , NY USA.
  • Zhao G; a Lindsley F. Kimball Research Institute; New York Blood Center ; New York , NY USA.
  • Zhou Y; d Key Lab of New Drug Screening of Guangdong Province; School of Pharmaceutical Sciences; Southern Medical University ; Guangzhou , China.
  • Du L; c State Key Laboratory of Pathogen and Biosecurity; Beijing Institute of Microbiology and Epidemiology ; Beijing , China.
  • Jiang S; c State Key Laboratory of Pathogen and Biosecurity; Beijing Institute of Microbiology and Epidemiology ; Beijing , China.
Hum Vaccin Immunother ; 11(12): 2831-8, 2015.
Article in En | MEDLINE | ID: mdl-26260706
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin Fc Fragments / Influenza Vaccines / Vaccines, Synthetic / Hemagglutinin Glycoproteins, Influenza Virus / Influenza A Virus, H5N1 Subtype / Antibodies, Neutralizing / Antibodies, Viral Limits: Animals / Female / Humans Language: En Journal: Hum Vaccin Immunother Year: 2015 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin Fc Fragments / Influenza Vaccines / Vaccines, Synthetic / Hemagglutinin Glycoproteins, Influenza Virus / Influenza A Virus, H5N1 Subtype / Antibodies, Neutralizing / Antibodies, Viral Limits: Animals / Female / Humans Language: En Journal: Hum Vaccin Immunother Year: 2015 Document type: Article Country of publication: United States