Identification of two essential aspartates for polymerase activity in parainfluenza virus L protein by a minireplicon system expressing secretory luciferase.

Matsumoto, Yusuke; Ohta, Keisuke; Yumine, Natsuko; Goto, Hideo; Nishio, Machiko

Matsumoto, Yusuke; Ohta, Keisuke; Yumine, Natsuko; Goto, Hideo; Nishio, Machiko.

Affiliation

Matsumoto Y; Department of Microbiology, School of Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Ohta K; Department of Microbiology, School of Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Yumine N; Department of Microbiology, School of Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Goto H; Department of Microbiology, School of Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Nishio M; Department of Microbiology, School of Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.

Microbiol Immunol ; 59(11): 676-83, 2015 Nov.

Article in En | MEDLINE | ID: mdl-26446904

Subject(s)

Aspartic Acid/genetics; Copepoda/enzymology; Luciferases/metabolism; Parainfluenza Virus 2, Human/enzymology; Parainfluenza Virus 2, Human/metabolism; Transfection/methods; Viral Proteins/genetics; Viral Proteins/physiology; Virus Replication/physiology; Animals; Cells, Cultured; Conserved Sequence; Humans

Key words

L protein; minireplicon system; parainfluenza virus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Virus Replication / Transfection / Aspartic Acid / Parainfluenza Virus 2, Human / Copepoda / Luciferases Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Microbiol Immunol Year: 2015 Document type: Article Affiliation country: Japan Country of publication: Australia

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