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Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism.
Wigerblad, Gustaf; Bas, Duygu B; Fernades-Cerqueira, Cátia; Krishnamurthy, Akilan; Nandakumar, Kutty Selva; Rogoz, Katarzyna; Kato, Jungo; Sandor, Katalin; Su, Jie; Jimenez-Andrade, Juan Miguel; Finn, Anja; Bersellini Farinotti, Alex; Amara, Khaled; Lundberg, Karin; Holmdahl, Rikard; Jakobsson, Per-Johan; Malmström, Vivianne; Catrina, Anca I; Klareskog, Lars; Svensson, Camilla I.
Affiliation
  • Wigerblad G; Molecular Pain Research, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Bas DB; Molecular Pain Research, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Fernades-Cerqueira C; Rheumatology Unit, Department of Medicine, Karolinska Institutet, CMM, Karolinska University Hospital Solna, Stockholm, Sweden.
  • Krishnamurthy A; Rheumatology Unit, Department of Medicine, Karolinska Institutet, CMM, Karolinska University Hospital Solna, Stockholm, Sweden.
  • Nandakumar KS; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Rogoz K; Molecular Pain Research, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Kato J; Molecular Pain Research, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Sandor K; Molecular Pain Research, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Su J; Molecular Pain Research, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Jimenez-Andrade JM; Department of Unidad Academica Multidisciplinaria Reynosa Aztlan, Universidad Autonoma de Tamaulipas, Reynosa, Tamaulipas, Mexico.
  • Finn A; Molecular Pain Research, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Bersellini Farinotti A; Molecular Pain Research, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Amara K; Rheumatology Unit, Department of Medicine, Karolinska Institutet, CMM, Karolinska University Hospital Solna, Stockholm, Sweden.
  • Lundberg K; Rheumatology Unit, Department of Medicine, Karolinska Institutet, CMM, Karolinska University Hospital Solna, Stockholm, Sweden.
  • Holmdahl R; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Jakobsson PJ; Rheumatology Unit, Department of Medicine, Karolinska Institutet, CMM, Karolinska University Hospital Solna, Stockholm, Sweden.
  • Malmström V; Rheumatology Unit, Department of Medicine, Karolinska Institutet, CMM, Karolinska University Hospital Solna, Stockholm, Sweden.
  • Catrina AI; Rheumatology Unit, Department of Medicine, Karolinska Institutet, CMM, Karolinska University Hospital Solna, Stockholm, Sweden.
  • Klareskog L; Rheumatology Unit, Department of Medicine, Karolinska Institutet, CMM, Karolinska University Hospital Solna, Stockholm, Sweden.
  • Svensson CI; Molecular Pain Research, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Ann Rheum Dis ; 75(4): 730-8, 2016 Apr.
Article in En | MEDLINE | ID: mdl-26613766
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoclasts / Autoantibodies / Interleukin-8 / Citrulline / Arthralgia / Chemokine CXCL1 / Nociception Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Ann Rheum Dis Year: 2016 Document type: Article Affiliation country: Sweden Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoclasts / Autoantibodies / Interleukin-8 / Citrulline / Arthralgia / Chemokine CXCL1 / Nociception Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Ann Rheum Dis Year: 2016 Document type: Article Affiliation country: Sweden Country of publication: United kingdom