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The impact of genetic polymorphisms on the pharmacokinetics of efavirenz in African children.
Bienczak, Andrzej; Cook, Adrian; Wiesner, Lubbe; Olagunju, Adeniyi; Mulenga, Veronica; Kityo, Cissy; Kekitiinwa, Addy; Owen, Andrew; Walker, A Sarah; Gibb, Diana M; McIlleron, Helen; Burger, David; Denti, Paolo.
Affiliation
  • Bienczak A; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.
  • Cook A; MRC Clinical Trials Unit at University College London, London, UK.
  • Wiesner L; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.
  • Olagunju A; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.
  • Mulenga V; University Teaching Hospital, Department of Paediatrics and Child Health, Lusaka, Zambia.
  • Kityo C; Joint Clinical Research Centre, Kampala, Uganda.
  • Kekitiinwa A; Baylor College of Medicine Bristol Myers Squibb Children's Clinical Centre of Excellence, Kampala, Uganda / Gulu Regional Centre of Excellence, Gulu, Uganda.
  • Owen A; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.
  • Walker AS; MRC Clinical Trials Unit at University College London, London, UK.
  • Gibb DM; MRC Clinical Trials Unit at University College London, London, UK.
  • McIlleron H; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.
  • Burger D; Department of Pharmacy, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.
  • Denti P; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.
Br J Clin Pharmacol ; 82(1): 185-98, 2016 07.
Article in En | MEDLINE | ID: mdl-26991336
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Reverse Transcriptase Inhibitors / Benzoxazines / Cytochrome P-450 CYP2B6 / Models, Biological Type of study: Guideline / Prognostic_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Country/Region as subject: Africa Language: En Journal: Br J Clin Pharmacol Year: 2016 Document type: Article Affiliation country: South Africa Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Reverse Transcriptase Inhibitors / Benzoxazines / Cytochrome P-450 CYP2B6 / Models, Biological Type of study: Guideline / Prognostic_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Country/Region as subject: Africa Language: En Journal: Br J Clin Pharmacol Year: 2016 Document type: Article Affiliation country: South Africa Country of publication: United kingdom