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Plasmin is a natural trigger for bradykinin production in patients with hereditary angioedema with factor XII mutations.
de Maat, Steven; Björkqvist, Jenny; Suffritti, Chiara; Wiesenekker, Chantal P; Nagtegaal, Willem; Koekman, Arnold; van Dooremalen, Sanne; Pasterkamp, Gerard; de Groot, Philip G; Cicardi, Marco; Renné, Thomas; Maas, Coen.
Affiliation
  • de Maat S; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Björkqvist J; Department of Molecular Medicine and Surgery, Karolinska Institutet and University Hospital, Solna, Sweden; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Suffritti C; Department of Biomedical and Clinical Sciences, Luigi Sacco, University of Milan, and Luigi Sacco Hospital Milan, Milan, Italy.
  • Wiesenekker CP; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Nagtegaal W; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Koekman A; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • van Dooremalen S; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Pasterkamp G; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • de Groot PG; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Cicardi M; Department of Biomedical and Clinical Sciences, Luigi Sacco, University of Milan, and Luigi Sacco Hospital Milan, Milan, Italy.
  • Renné T; Department of Molecular Medicine and Surgery, Karolinska Institutet and University Hospital, Solna, Sweden; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Maas C; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address: cmaas4@umcutrecht.nl.
J Allergy Clin Immunol ; 138(5): 1414-1423.e9, 2016 11.
Article in En | MEDLINE | ID: mdl-27130860

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Factor XII / Bradykinin / Fibrinolysin / Angioedemas, Hereditary Type of study: Prognostic_studies Limits: Female / Humans / Pregnancy Language: En Journal: J Allergy Clin Immunol Year: 2016 Document type: Article Affiliation country: Netherlands Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Factor XII / Bradykinin / Fibrinolysin / Angioedemas, Hereditary Type of study: Prognostic_studies Limits: Female / Humans / Pregnancy Language: En Journal: J Allergy Clin Immunol Year: 2016 Document type: Article Affiliation country: Netherlands Country of publication: United States