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Repurposing the Nonsteroidal Anti-inflammatory Drug Diflunisal as an Osteoprotective, Antivirulence Therapy for Staphylococcus aureus Osteomyelitis.
Hendrix, Andrew S; Spoonmore, Thomas J; Wilde, Aimee D; Putnam, Nicole E; Hammer, Neal D; Snyder, Daniel J; Guelcher, Scott A; Skaar, Eric P; Cassat, James E.
Affiliation
  • Hendrix AS; Department of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Spoonmore TJ; Department of Chemical and Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA.
  • Wilde AD; Department of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Putnam NE; Department of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Hammer ND; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Snyder DJ; Department of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Guelcher SA; Department of Chemical and Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA Vanderbilt Center for Bone Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Skaar EP; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Cassat JE; Department of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA Vanderbilt Center for Bone Biology, Vanderbilt U
Antimicrob Agents Chemother ; 60(9): 5322-30, 2016 09.
Article in En | MEDLINE | ID: mdl-27324764

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteomyelitis / Staphylococcal Infections / Diflunisal / Delayed-Action Preparations / Bone Density Conservation Agents / Drug Repositioning / Anti-Bacterial Agents Limits: Animals / Female / Humans Language: En Journal: Antimicrob Agents Chemother Year: 2016 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteomyelitis / Staphylococcal Infections / Diflunisal / Delayed-Action Preparations / Bone Density Conservation Agents / Drug Repositioning / Anti-Bacterial Agents Limits: Animals / Female / Humans Language: En Journal: Antimicrob Agents Chemother Year: 2016 Document type: Article Affiliation country: United States Country of publication: United States