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Complexation of clofazimine by macrocyclic cucurbit[7]uril reduced its cardiotoxicity without affecting the antimycobacterial efficacy.
Li, Shengke; Chan, Judy Yuet-Wa; Li, Yan; Bardelang, David; Zheng, Jun; Yew, Wing Wai; Chan, Denise Pui-Chung; Lee, Simon Ming Yuen; Wang, Ruibing.
Affiliation
  • Li S; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau SAR, China. rwang@umac.mo.
Org Biomol Chem ; 14(31): 7563-9, 2016 Aug 21.
Article in En | MEDLINE | ID: mdl-27439674
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bridged-Ring Compounds / Clofazimine / Mycobacterium smegmatis / Macrocyclic Compounds / Imidazoles / Anti-Bacterial Agents Limits: Animals Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2016 Document type: Article Affiliation country: China Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bridged-Ring Compounds / Clofazimine / Mycobacterium smegmatis / Macrocyclic Compounds / Imidazoles / Anti-Bacterial Agents Limits: Animals Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2016 Document type: Article Affiliation country: China Country of publication: United kingdom