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Analogues of Marine Guanidine Alkaloids Are in Vitro Effective against Trypanosoma cruzi and Selectively Eliminate Leishmania (L.) infantum Intracellular Amastigotes.
Martins, Ligia F; Mesquita, Juliana T; Pinto, Erika G; Costa-Silva, Thais A; Borborema, Samanta E T; Galisteo Junior, Andres J; Neves, Bruno J; Andrade, Carolina H; Shuhaib, Zainab Al; Bennett, Elliot L; Black, Gregory P; Harper, Philip M; Evans, Daniel M; Fituri, Hisham S; Leyland, John P; Martin, Claire; Roberts, Terence D; Thornhill, Andrew J; Vale, Stephen A; Howard-Jones, Andrew; Thomas, Dafydd A; Williams, Harri L; Overman, Larry E; Berlinck, Roberto G S; Murphy, Patrick J; Tempone, Andre G.
Affiliation
  • Martins LF; Centre for Parasitology and Mycology, Instituto Adolfo Lutz , Avenida Dr. Arnaldo, 351, 8° andar, 01246-000 São Paulo, SP, Brazil.
  • Mesquita JT; Centre for Parasitology and Mycology, Instituto Adolfo Lutz , Avenida Dr. Arnaldo, 351, 8° andar, 01246-000 São Paulo, SP, Brazil.
  • Pinto EG; Centre for Parasitology and Mycology, Instituto Adolfo Lutz , Avenida Dr. Arnaldo, 351, 8° andar, 01246-000 São Paulo, SP, Brazil.
  • Costa-Silva TA; Instituto de Medicina Tropical, Universidade de São Paulo , Avenida Dr. Enéas de Carvalho Aguiar, 470, 05403-000 São Paulo, SP, Brazil.
  • Borborema SE; Centre for Parasitology and Mycology, Instituto Adolfo Lutz , Avenida Dr. Arnaldo, 351, 8° andar, 01246-000 São Paulo, SP, Brazil.
  • Galisteo Junior AJ; Centre for Parasitology and Mycology, Instituto Adolfo Lutz , Avenida Dr. Arnaldo, 351, 8° andar, 01246-000 São Paulo, SP, Brazil.
  • Neves BJ; Instituto de Medicina Tropical, Universidade de São Paulo , Avenida Dr. Enéas de Carvalho Aguiar, 470, 05403-000 São Paulo, SP, Brazil.
  • Andrade CH; LabMol, Laboratory for Molecular Modeling and Drug Design, Faculdade de Farmácia, Universidade Federal de Goiás , Goiânia, Brazil.
  • Shuhaib ZA; LabMol, Laboratory for Molecular Modeling and Drug Design, Faculdade de Farmácia, Universidade Federal de Goiás , Goiânia, Brazil.
  • Bennett EL; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Black GP; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Harper PM; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Evans DM; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Fituri HS; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Leyland JP; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Martin C; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Roberts TD; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Thornhill AJ; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Vale SA; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Howard-Jones A; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Thomas DA; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Williams HL; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Overman LE; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
  • Berlinck RG; University of California, Irvine , 4042A Frederick Reines Hall, Irvine, California 92697, United States.
  • Murphy PJ; Instituto de Química de São Carlos, Universidade de São Paulo , CP 780, CEP 13560-970, São Carlos, SP, Brazil.
  • Tempone AG; School of Chemistry, Bangor University , Bangor, Gwynedd, Wales, U.K. LL57 2UW.
J Nat Prod ; 79(9): 2202-10, 2016 09 23.
Article in En | MEDLINE | ID: mdl-27586460
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Porifera / Trypanosoma cruzi / Leishmania infantum / Guanidines Limits: Animals Language: En Journal: J Nat Prod Year: 2016 Document type: Article Affiliation country: Brazil Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Porifera / Trypanosoma cruzi / Leishmania infantum / Guanidines Limits: Animals Language: En Journal: J Nat Prod Year: 2016 Document type: Article Affiliation country: Brazil Country of publication: United States