Your browser doesn't support javascript.
loading
Structure-based design and SAR development of 5,6-dihydroimidazolo[1,5-f]pteridine derivatives as novel Polo-like kinase-1 inhibitors.
Kiryanov, Andre; Natala, Srinivasa; Jones, Benjamin; McBride, Christopher; Feher, Victoria; Lam, Betty; Liu, Yan; Honda, Kouhei; Uchiyama, Noriko; Kawamoto, Tomohiro; Hikichi, Yuichi; Zhang, Lilly; Hosfield, David; Skene, Robert; Zou, Hua; Stafford, Jeffrey; Cao, Xiaodong; Ichikawa, Takashi.
Affiliation
  • Kiryanov A; Takeda California, 10410 Science Center Drive, San Diego 92121, USA. Electronic address: andre.kiryanov@takeda.com.
  • Natala S; Takeda California, 10410 Science Center Drive, San Diego 92121, USA.
  • Jones B; Takeda California, 10410 Science Center Drive, San Diego 92121, USA.
  • McBride C; Takeda California, 10410 Science Center Drive, San Diego 92121, USA.
  • Feher V; Takeda California, 10410 Science Center Drive, San Diego 92121, USA.
  • Lam B; Takeda California, 10410 Science Center Drive, San Diego 92121, USA.
  • Liu Y; Takeda California, 10410 Science Center Drive, San Diego 92121, USA.
  • Honda K; Takeda Pharmaceutical Company, Ltd, 2-26-1, Muraokahigashi, Fujisawa, Kanagawa 251-855, Japan.
  • Uchiyama N; Takeda Pharmaceutical Company, Ltd, 2-26-1, Muraokahigashi, Fujisawa, Kanagawa 251-855, Japan.
  • Kawamoto T; Takeda Pharmaceutical Company, Ltd, 2-26-1, Muraokahigashi, Fujisawa, Kanagawa 251-855, Japan.
  • Hikichi Y; Takeda Pharmaceutical Company, Ltd, 2-26-1, Muraokahigashi, Fujisawa, Kanagawa 251-855, Japan.
  • Zhang L; Takeda California, 10410 Science Center Drive, San Diego 92121, USA.
  • Hosfield D; Takeda California, 10410 Science Center Drive, San Diego 92121, USA.
  • Skene R; Takeda California, 10410 Science Center Drive, San Diego 92121, USA.
  • Zou H; Takeda California, 10410 Science Center Drive, San Diego 92121, USA.
  • Stafford J; Takeda California, 10410 Science Center Drive, San Diego 92121, USA.
  • Cao X; Takeda California, 10410 Science Center Drive, San Diego 92121, USA.
  • Ichikawa T; Takeda Pharmaceutical Company, Ltd, 2-26-1, Muraokahigashi, Fujisawa, Kanagawa 251-855, Japan.
Bioorg Med Chem Lett ; 27(5): 1311-1315, 2017 03 01.
Article in En | MEDLINE | ID: mdl-28169164
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pteridines / Drug Design / Proto-Oncogene Proteins / Protein Serine-Threonine Kinases / Cell Cycle Proteins / Imidazoles Limits: Animals / Female / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2017 Document type: Article Country of publication: United kingdom
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pteridines / Drug Design / Proto-Oncogene Proteins / Protein Serine-Threonine Kinases / Cell Cycle Proteins / Imidazoles Limits: Animals / Female / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2017 Document type: Article Country of publication: United kingdom