Synthesis, antimicrobial, cytotoxic and E. coli DNA gyrase inhibitory activities of coumarinyl amino alcohols.

Singh, Vineeta; Katiyar, Diksha

Singh, Vineeta; Katiyar, Diksha.

Affiliation

Priyanka; Department of Chemistry, MMV, Banaras Hindu University, Varanasi 221005, India.
Singh V; Department of Biotechnology, Institute of Engineering and Technology, Lucknow 226021, India.
Ekta; Department of Bioinformatics, MMV, Banaras Hindu University, Varanasi 221005, India.
Katiyar D; Department of Chemistry, MMV, Banaras Hindu University, Varanasi 221005, India. Electronic address: dikshakatiyar@gmail.com.

Bioorg Chem ; 71: 120-127, 2017 04.

Article in En | MEDLINE | ID: mdl-28196603

Subject(s)

Amino Alcohols/chemistry; Amino Alcohols/pharmacology; Anti-Infective Agents/chemistry; Anti-Infective Agents/pharmacology; DNA Gyrase/metabolism; Escherichia coli/enzymology; Topoisomerase II Inhibitors/chemistry; Topoisomerase II Inhibitors/pharmacology; Amino Alcohols/chemical synthesis; Anti-Bacterial Agents/chemical synthesis; Anti-Bacterial Agents/chemistry; Anti-Bacterial Agents/pharmacology; Anti-Infective Agents/chemical synthesis; Bacteria/drug effects; Bacteria/enzymology; Bacterial Infections/drug therapy; Bacterial Infections/microbiology; Coumarins/chemical synthesis; Coumarins/chemistry; Coumarins/pharmacology; Escherichia coli/drug effects; Escherichia coli Infections/drug therapy; Escherichia coli Infections/microbiology; Fungi/drug effects; Fungi/enzymology; Humans; Microbial Sensitivity Tests; Models, Molecular; Mycoses/drug therapy; Mycoses/microbiology; Topoisomerase II Inhibitors/chemical synthesis

Key words

Antibacterial; Coumarins; Gram negative; Gyrase

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Gyrase / Escherichia coli / Topoisomerase II Inhibitors / Amino Alcohols / Anti-Infective Agents Limits: Humans Language: En Journal: Bioorg Chem Year: 2017 Document type: Article Affiliation country: India Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google