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HIV Tat protein and amyloid-ß peptide form multifibrillar structures that cause neurotoxicity.
Hategan, Alina; Bianchet, Mario A; Steiner, Joseph; Karnaukhova, Elena; Masliah, Eliezer; Fields, Adam; Lee, Myoung-Hwa; Dickens, Alex M; Haughey, Norman; Dimitriadis, Emilios K; Nath, Avindra.
Affiliation
  • Hategan A; Section of Infections of the Nervous System, National Institute for Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.
  • Bianchet MA; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
  • Steiner J; Structural Enzymology and Thermodynamics Group, Department of Biophysics and Biophysical Chemistry, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
  • Karnaukhova E; Section of Infections of the Nervous System, National Institute for Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.
  • Masliah E; Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.
  • Fields A; Department of Pathology, University of California at San Diego, San Diego, California, USA.
  • Lee MH; Department of Pathology, University of California at San Diego, San Diego, California, USA.
  • Dickens AM; Section of Infections of the Nervous System, National Institute for Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.
  • Haughey N; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
  • Dimitriadis EK; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
  • Nath A; Scanning Probe Microscopy Unit, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA.
Nat Struct Mol Biol ; 24(4): 379-386, 2017 04.
Article in En | MEDLINE | ID: mdl-28218748

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Amyloid beta-Peptides / Tat Gene Products, Human Immunodeficiency Virus / Amyloid / Neurotoxins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Struct Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2017 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Amyloid beta-Peptides / Tat Gene Products, Human Immunodeficiency Virus / Amyloid / Neurotoxins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Struct Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2017 Document type: Article Affiliation country: United States Country of publication: United States