Genetic Polymorphism of Drug-Metabolizing Enzymes CYP2C9 and CYP2C19 in Moroccan Population.

Afilal, Driss; Basselam, Mohamed Amine; Brakez, Zahra; Chouham, Said; Brehm, António; Izaabel, El Hassan

Afilal, Driss; Basselam, Mohamed Amine; Brakez, Zahra; Chouham, Said; Brehm, António; Izaabel, El Hassan.

Affiliation

Afilal D; 1 Cellular Biology and Molecular Genetics Laboratory, Faculty of Sciences, University Ibn-Zohr , Agadir, Morocco .
Basselam MA; 1 Cellular Biology and Molecular Genetics Laboratory, Faculty of Sciences, University Ibn-Zohr , Agadir, Morocco .
Brakez Z; 1 Cellular Biology and Molecular Genetics Laboratory, Faculty of Sciences, University Ibn-Zohr , Agadir, Morocco .
Chouham S; 1 Cellular Biology and Molecular Genetics Laboratory, Faculty of Sciences, University Ibn-Zohr , Agadir, Morocco .
Brehm A; 2 Human Genetics Laboratory, Life Sciences Faculty, University of Madeira , Funchal, Portugal .
Izaabel EH; 1 Cellular Biology and Molecular Genetics Laboratory, Faculty of Sciences, University Ibn-Zohr , Agadir, Morocco .

Genet Test Mol Biomarkers ; 21(5): 298-304, 2017 May.

Article in En | MEDLINE | ID: mdl-28282224

Subject(s)

Cytochrome P-450 CYP2C19/genetics; Cytochrome P-450 CYP2C9/genetics; Adult; Alleles; Aryl Hydrocarbon Hydroxylases/genetics; Cytochrome P-450 CYP2C19/metabolism; Cytochrome P-450 CYP2C9/metabolism; Female; Gene Frequency/genetics; Genetics, Population; Genotype; Humans; Male; Morocco; Mutation; Phenotype; Polymerase Chain Reaction; Polymorphism, Genetic/genetics; Young Adult

Key words

CYP2C9 and CYP2C19 genes; South Moroccan population; drug metabolism; individual and interethnic variability; poor metabolizer (PM) phenotype

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 CYP2C9 / Cytochrome P-450 CYP2C19 Limits: Adult / Female / Humans / Male Country/Region as subject: Africa Language: En Journal: Genet Test Mol Biomarkers Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2017 Document type: Article Affiliation country: Morocco Country of publication: United States

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