A consensus-hemagglutinin-based vaccine delivered by an attenuated Salmonella mutant protects chickens against heterologous H7N1 influenza virus.

Hyoung, Kim Je; Hajam, Irshad Ahmed; Lee, John Hwa

Hyoung, Kim Je; Hajam, Irshad Ahmed; Lee, John Hwa.

Affiliation

Hyoung KJ; College of Veterinary Medicine, Chonbuk National University, Iksan Campus, Iksan 54596, Republic of Korea.
Hajam IA; College of Veterinary Medicine, Chonbuk National University, Iksan Campus, Iksan 54596, Republic of Korea.
Lee JH; College of Veterinary Medicine, Chonbuk National University, Iksan Campus, Iksan 54596, Republic of Korea.

Oncotarget ; 8(24): 38780-38792, 2017 Jun 13.

Article in En | MEDLINE | ID: mdl-28418904

Subject(s)

Hemagglutinins/immunology; Influenza A virus/immunology; Influenza Vaccines/administration & dosage; Mutation; Orthomyxoviridae Infections/prevention & control; Salmonella/immunology; Animals; Antibodies, Viral/blood; Antibodies, Viral/immunology; Cells, Cultured; Chickens; Consensus; Female; Influenza A virus/classification; Influenza Vaccines/immunology; Orthomyxoviridae Infections/immunology; Orthomyxoviridae Infections/virology; Phylogeny; Salmonella/genetics; T-Lymphocytes/immunology; Vaccination; Virus Shedding

Key words

Salmonella Typhimurium; cell mediated immunity; hemagglutinin; humoral immunity; influenza

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Influenza A virus / Salmonella / Influenza Vaccines / Orthomyxoviridae Infections / Hemagglutinins / Mutation Type of study: Guideline Limits: Animals Language: En Journal: Oncotarget Year: 2017 Document type: Article Country of publication: United States

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