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A nonsense mutation in TLR5 is associated with survival and reduced IL-10 and TNF-α levels in human melioidosis.
Chaichana, Panjaporn; Chantratita, Narisara; Brod, Florian; Koosakulnirand, Sirikamon; Jenjaroen, Kemajittra; Chumseng, Suchintana; Sumonwiriya, Manutsanun; Burtnick, Mary N; Brett, Paul J; Teparrukkul, Prapit; Limmathurotsakul, Direk; Day, Nicholas P J; Dunachie, Susanna J; West, T Eoin.
Affiliation
  • Chaichana P; Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
  • Chantratita N; Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
  • Brod F; Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
  • Koosakulnirand S; Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
  • Jenjaroen K; Jenner Institute, University of Oxford, Oxford, United Kingdom.
  • Chumseng S; Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand.
  • Sumonwiriya M; Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
  • Burtnick MN; Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
  • Brett PJ; Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
  • Teparrukkul P; Department of Microbiology and Immunology, University of South Alabama, Mobile, AL, United States of America.
  • Limmathurotsakul D; Department of Microbiology and Immunology, University of South Alabama, Mobile, AL, United States of America.
  • Day NPJ; Sappasithiprasong Hospital, Ubon Ratchathani, Thailand.
  • Dunachie SJ; Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
  • West TE; Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
PLoS Negl Trop Dis ; 11(5): e0005587, 2017 May.
Article in En | MEDLINE | ID: mdl-28475641
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Necrosis Factor-alpha / Burkholderia pseudomallei / Interleukin-10 / Codon, Nonsense / Genetic Predisposition to Disease / Toll-Like Receptor 5 / Melioidosis Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: PLoS Negl Trop Dis Journal subject: MEDICINA TROPICAL Year: 2017 Document type: Article Affiliation country: Thailand Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Necrosis Factor-alpha / Burkholderia pseudomallei / Interleukin-10 / Codon, Nonsense / Genetic Predisposition to Disease / Toll-Like Receptor 5 / Melioidosis Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: PLoS Negl Trop Dis Journal subject: MEDICINA TROPICAL Year: 2017 Document type: Article Affiliation country: Thailand Country of publication: United States