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TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections.

Biochimie; 142: 1-10, 2017 Nov.
Article in English | MEDLINE | ID: mdl-28778717
Influenza virus and coronavirus epidemics or pandemics have occurred in succession worldwide throughout the early 21st century. These epidemics or pandemics pose a major threat to human health. Here, we outline a critical role of the host cell protease TMPRSS2 in influenza virus and coronavirus infections and highlight an antiviral therapeutic strategy targeting TMPRSS2.