Inhibition of Wnt/ß-catenin by anthelmintic drug niclosamide effectively targets growth, survival, and angiogenesis of retinoblastoma.

Li, Zhi; Li, Qin; Wang, Genguo; Huang, Yi; Mao, Xiaochun; Zhang, Yanfang; Wang, Xueyan

Li, Zhi; Li, Qin; Wang, Genguo; Huang, Yi; Mao, Xiaochun; Zhang, Yanfang; Wang, Xueyan.

Affiliation

Li Z; Department of Ophthalmology, Xiangyang Central Hospital, Hospital Affiliated to Hubei University of Arts and ScienceXiangyang 441021, Hubei, People's Republic of China.
Li Q; Department of Ophthalmology, Xiangyang Central Hospital, Hospital Affiliated to Hubei University of Arts and ScienceXiangyang 441021, Hubei, People's Republic of China.
Wang G; Department of Ophthalmology, Xiangyang Central Hospital, Hospital Affiliated to Hubei University of Arts and ScienceXiangyang 441021, Hubei, People's Republic of China.
Huang Y; Department of Ophthalmology, Xiangyang Central Hospital, Hospital Affiliated to Hubei University of Arts and ScienceXiangyang 441021, Hubei, People's Republic of China.
Mao X; Department of Ophthalmology, Xiangyang Central Hospital, Hospital Affiliated to Hubei University of Arts and ScienceXiangyang 441021, Hubei, People's Republic of China.
Zhang Y; Department of Ophthalmology, Xiangyang Central Hospital, Hospital Affiliated to Hubei University of Arts and ScienceXiangyang 441021, Hubei, People's Republic of China.
Wang X; Department of Ophthalmology, Xiangyang Central Hospital, Hospital Affiliated to Hubei University of Arts and ScienceXiangyang 441021, Hubei, People's Republic of China.

Am J Transl Res ; 9(8): 3776-3786, 2017.

Article in En | MEDLINE | ID: mdl-28861168

Key words

Niclosamide; Wnt/ß-catenin; angiogenesis; chemotherapy; retinoblastoma

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Am J Transl Res Year: 2017 Document type: Article Country of publication: United States

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